Every claim on this site traces back to a published study. Here they all are — what each one tested, how strong the evidence is, and what it found in plain English.
A new low-dose minocycline (40 mg) outperformed both doxycycline 40 mg and placebo for rosacea.
Four combined 1440/1927 nm sessions improved wrinkles, tone, texture, and pores across diverse skin types.
Topical hyaluronic acid consistently improves skin hydration and, at lower molecular weights, the look of fine lines and skin quality.
Non-drowsy antihistamines are first-line for hives, with higher doses and omalizumab as next steps.
Several topical and oral treatments help perioral dermatitis, but the overall quality of evidence is limited.
The strongest evidence points to misuse of topical steroids as the main driver of perioral dermatitis.
Low-dose doxycycline roughly halved the relapse rate of rosacea bumps versus placebo.
Reviews how niacinamide supports skin energy, reduces inflammation, strengthens the barrier, and limits pigment transfer.
Strong evidence supports topical brimonidine for redness and azelaic acid and ivermectin for bumps and pimples.
Rosacea should be classified and treated by its individual features (phenotypes), aiming for completely clear skin.
Low-dose doxycycline (40 mg) worked about as well as minocycline (100 mg) for rosacea and caused fewer side effects.
Raising the antihistamine dose helped some people with chronic hives, mainly by reducing itch.
35% glycolic acid peels improved melasma about as well as salicylic-mandelic peels, and better than phytic acid peels.
Ivermectin cream kept rosacea clear longer than metronidazole after treatment stopped.
Ketoconazole and ciclopirox antifungals clear seborrheic dermatitis better than a dummy treatment.
Filler blocking a blood vessel can rarely cause blindness; the brow, nose, and smile lines are highest risk.
Oral nicotinamide 500 mg twice daily cut new non-melanoma skin cancers by about 23% versus placebo.
Topical steroids, and to some extent calcineurin inhibitors and lithium, reduce seborrheic dermatitis symptoms short-term.
Solid evidence supports IPL for sun spots, facial redness, telangiectasia, and rosacea.
Four low-energy 1440 nm sessions gave mild gains in texture, tone, and fine lines, with no lasting harm.
Ivermectin 1% cream stayed safe and effective for up to a year of treatment.
Omalizumab injections greatly reduced itch and welts in people with chronic hives that had not responded to antihistamines.
Adults using daily sunscreen showed about 24% less skin aging than those using it only when they chose to.
Salicylic acid modestly improves wart clearance, and cryotherapy was not clearly better than salicylic acid.
Topical hyaluronic acid improved skin hydration and elasticity, and lower-molecular-weight forms reduced wrinkle depth around the eyes.
Freezing and salicylic acid cleared plantar (foot) warts at similar rates.
Adults assigned to daily sunscreen had about half the rate of new melanoma over 10 years of follow-up.
Pimecrolimus cream improved perioral dermatitis faster than an inactive cream, especially in people whose rash followed steroid use.
Three Fraxel sessions improved atrophic acne scars by 51–75% in nearly 9 out of 10 patients.
Once-daily 40 mg doxycycline reduced rosacea bumps more than placebo, with side effects similar to placebo.
Topical 5% niacinamide reduced fine lines, wrinkles, dark spots, and red blotchiness over 12 weeks.
IPL added to hydroquinone faded stubborn melasma more than cream alone, but some pigment returned.
The original study introducing fractional laser treatment; it safely smoothed skin and improved wrinkles.
Hyaluronic acid filler lasted longer and needed less product than older collagen filler for smile lines.
A very low 20 mg twice-daily dose improved moderate acne without changing skin bacteria's antibiotic resistance.
Niacinamide boosted skin's production of ceramides and other barrier fats and lowered water loss through the skin.
8% glycolic acid cream modestly improved signs of sun-damaged skin and was well tolerated.
4% nicotinamide gel worked about as well as 1% clindamycin gel for inflammatory acne over 8 weeks.