Comparison

Dysport vs Botox

Same toxin, two brands. What each is approved to treat, why “cheaper per unit” is not cheaper, and the allergy that rules one out.
Written & medically reviewed by the Dermapedia team
At a Glance

The toxin itself is the same molecule in both products. It does not travel through your skin naked, though. It comes wrapped in a set of helper proteins, and that wrapper makes them different:

Botox's protein wrappers are heavy and uniform (~900 kDa). So when you inject a heavy molecule, it tends to stay right near the injection site. This is better for treating small areas with tiny muscles (like around the eye).

Dysport's protein wrappers vary in size (~500 to 900 kDa). This makes Dysport smaller and lighter. It is able to spread farther in the skin. This is better for treating large areas (like the forehead).

Dysport
abobotulinumtoxinA
Botox
onabotulinumtoxinA
Dysport's protein wrapper comes in a range of sizes, so the bundles are not all the same weight. The lighter molecules can travel farther in the skin. Remember, Dysport Diffuses!
Botox's protein wrapper is uniform — every bundle is the same weight. Botox is a heavy protein and tends to stay exactly where it's injected. Remember, Botox stays in a little Box!

What it is

Botulinum toxin type A

The same active protein as Botox. Different company, different recipe.

Botulinum toxin type A

The original. It has been used for wrinkles since 2002.

How the units work

50 units for frown lines

Five small injections.

20 units for frown lines

Also five small injections.

Both
A Dysport unit is not the same size as a Botox unit. They are two different measuring systems. This is the most misunderstood thing about the two brands.

How fast you see it

2 to 3 days
2 to 4 days
Both
Neither is instant. Book at least two weeks before an event, so there is time to fix anything uneven.

How long it lasts

About 3 to 4 months
About 3 to 4 months
Both
You will read that Dysport lasts longer. If it does, it is by about two weeks. Your muscle strength and your dose matter far more than the brand.

How much it spreads

Spreads more

Helpful across a wide forehead. Less helpful right above the brow, where spread is how you end up with a droopy eyelid.

Stays put a little better

Easier to keep inside one small muscle.

Both
Spreading is not good or bad on its own. It depends on the muscle being treated.

What it costs

Cheaper per unit, similar per visit

You need about two and a half times as many units, so the lower unit price mostly cancels out.

Higher per unit

Measured in bigger units, so the number looks bigger for the same treatment.

Both
The average botulinum toxin visit runs a few hundred dollars, and price varies a lot by city and injector.

Who should not have it

Anyone allergic to cow's milk protein

Dysport may contain traces of it. Also skip either one if you have an infection where the shot would go.

Fewer restrictions

No milk protein.

Both
This is the one difference that is a hard stop rather than a preference.

Who tends to be happy with it

Best for
Frown lines, especially with a wide or strong forehead.
The mindset
You want the wider spread working for you, not against you.
Best for
Small areas, and anywhere close to the eyebrow.
The mindset
You want the longest track record.
Both
If one has worked well for you, there is no reason to switch.
Diagram labelled Dysport: a red octagon marked TOXIN ringed by four navy circles marked PROTEIN, each a different size. Weight is given as 500 to 900 kDa.
Dysport's protein wrapper comes in a range of sizes, so the bundles are not all the same weight. The lighter molecules can travel farther in the skin. Remember, Dysport Diffuses!
Diagram labelled Botox: a red octagon marked TOXIN ringed by four navy circles marked PROTEIN, all the same size. Weight is given as 900 kDa.
Botox's protein wrapper is uniform — every bundle is the same weight. Botox is a heavy protein and tends to stay exactly where it's injected. Remember, Botox stays in a little Box!

What that means for your face

A 2025 trial measured it. One side of each person's forehead was treated with each product, and Dysport covered the larger area.

Neither behaviour is better on its own — but it is worth asking your injector which product they plan to use, and why. Close to the eyebrow, spread is exactly how you end up with a heavy or droopy lid.

An experienced injector matters more than the name on the vial.

Why "cheaper per unit" is not really cheaper

This is the number that trips up the most people.

A unit of Botox and a unit of Dysport are not the same amount of anything. They are two separate measuring systems, and both companies say so on their own FDA labels. Dysport's says its units cannot be converted into the units of any other botulinum toxin.

You can see the gap in the approved doses. For the same frown lines, on the same face, the dose is 20 units of Botox or 50 units of Dysport. Injectors work at roughly two and a half to three Dysport units for every one Botox unit.

So a clinic advertising Dysport at a third of the price per unit is not giving you a discount. It is quoting a smaller unit. Once you do the math, the two visits usually cost about the same.

Ask one question instead: what does the whole treatment cost? Any clinic should be able to tell you before you sit down.

Worth asking before you book

  • What does the whole treatment cost? Not the per-unit price.
  • How many units, and of which brand?
  • Have you injected this area with this brand before?
  • What happens if one side looks higher at two weeks?

That last one matters. A small difference between the two sides is common, and it is usually fixed with a few more units at the two-week mark. A clinic that includes that visit is worth more than one that is slightly cheaper.

Call your injector if

  • One eyelid starts to droop, or your vision changes
  • You have trouble swallowing, speaking, or breathing
  • You feel weakness somewhere you did not have treated

The last two are rare. Both products carry an FDA warning about the toxin travelling beyond the injection site, and symptoms can start hours or even weeks later. Get help the same day.

Questions people ask+
Is Dysport the same thing as Botox?Not the same product, but the same active ingredient. They are made by different companies, and they are measured in different units. Most people cannot tell the results apart.
Which one is cheaper?Per unit, Dysport. Per visit, they usually land close together. Dysport is measured in smaller units, so you need about two and a half times as many. Ask any clinic what the whole treatment costs, not what a unit costs.
Does Dysport really work faster?A little, maybe. Both start working in about two to four days. The difference is a day or two, not a week. Neither one is instant.
Which one lasts longer?Both run about three to four months. Dysport may last a couple of weeks longer, but your muscle strength and your dose affect this far more than the brand does.
Can I switch from Botox to Dysport?Yes, and plenty of people do. Your injector has to redo the math on the dose, because the units are not the same size. Tell them what you had last time and how long it lasted.
Can you use Dysport if you are allergic to milk?No. Dysport may contain traces of cow's milk protein, and a milk allergy is listed as a reason not to use it. Botox does not contain milk protein. Mention any food allergy before you are injected.
Is Dysport approved for crow's feet and forehead lines?No. In the United States, the only cosmetic use Dysport is approved for is the frown lines between the brows, in adults under 65. Botox is approved for four areas: frown lines, crow's feet, forehead lines, and neck bands. Injectors do use Dysport elsewhere, which is legal and common, but it is outside what the FDA reviewed.