Comparison

Ellanse vs Sculptra

Ellanse fills on the day and lasts one to three years by version. Sculptra shows nothing at first and builds collagen over a course of visits.
Written & medically reviewed by the Dermapedia team
At a Glance

Ellansé gives volume on the day and then builds collagen, and you pick how long it lasts. It is made of polycaprolactone beads in a gel, and the versions run from about a year to three years. Sculptra gives you nothing on the day and builds collagen slowly across a course of visits. Ellansé is not sold in the United States, so for many readers that settles the question before anything else does.

Ellansé
Also called Ellanse, polycaprolactone filler, PCL filler
Sculptra
Also called poly-L-lactic acid, PLLA, Sculptra Aesthetic

What is in the syringe

Polycaprolactone beads in a gel

Polycaprolactone is a soft, slowly dissolving material used in stitches and implants. The gel does the filling. The beads do the collagen work.

Poly-L-lactic acid in liquid

Also a stitch material. There is no gel to fill with, so nothing shows on the day.

Do you see anything on the day

Yes

The gel carrier fills straight away, then absorbs over a few months as collagen takes its place.

No

There is swelling from the fluid for a few days. Then you look much the same while collagen builds.

How long it lasts

One to three years, by version

The versions are named for how long the beads take to break down, and your injector picks one before treatment.

About two years

There is one version, so there is no length to choose.

How many visits

Often one

Sometimes a top-up later, though the point of the longer versions is not to come back.

Usually two to four

Spaced about a month apart. It is a course, not an appointment.

What it is used for

Volume and structure

Cheeks, temples, chin and jaw, and the folds running from nose to mouth.

Broad thinning

Hollow cheeks, temples and a face that has lost fullness everywhere at once. Also used on the body.

Where you can have it done

Europe and much of Asia

Ellansé is not sold in the United States, so US readers comparing the two are usually choosing between Sculptra and something else.

Widely available, including the US

It has been used for facial volume for around twenty years.

Can it be undone

No
No
Both
Neither dissolves, and Ellansé is the longer commitment. A hyaluronic acid filler can be dissolved, so it is the lower-risk way to find out what you like first.

Side effects to expect

Bruising, swelling, firm lumps

Lumps are the specific complaint with a long-lasting bead, and they cannot be dissolved away.

Bruising, swelling, tenderness

Small lumps here too. Massage afterwards is part of the instructions for that reason.

Both
The serious risk is rare and shared by both: product entering a blood vessel. Who injects you matters more than which product they use.

Cost

Priced per syringe, one visit

The longer-lasting versions usually cost more per syringe.

Priced per session, across a course

Ask what the whole plan costs, not what one session costs.

The at-home or drugstore version

There is not one

No cream carries a bead of anything under the skin, and nothing sold over the counter reaches the depth this works at.

There is not one either

Collagen creams and collagen drinks borrow the word. They do not build collagen in one chosen spot.

Who each suits

Best for
Someone who wants volume they can see today and does not want to come back for years.
The mindset
You are confident about the result, because you are living with it for a long time.
Best for
Volume loss across the whole face, and someone happy to wait.
The mindset
You want gradual change nobody can point to.

Both build collagen, but only one fills on the day

Ellansé does two jobs at once: The gel carrier gives volume immediately, and while that gel absorbs, the beads prompt your skin to lay down its own collagen. The result hands over from one to the other.

Sculptra only does the second job: There is no lasting gel in it, so the entire result is collagen you grew yourself. That is why the wait is two to three months.

This is the practical difference between them: If seeing a change on the day matters to you, that is one product. If you would rather nobody noticed a change happening, that is the other.

Choosing a longer version is a bigger decision than it sounds

A three-year product is three years of a result you may not want: Neither of these can be dissolved, so the length you pick is the length you are committed to.

Faces also change during those years: Volume placed to suit you now sits in a slightly different face later, which is a reason injectors often start with a shorter version.

Longer-lasting is only an advantage if you like the result: That sentence is worth reading twice before you agree to the version that lasts longest.

What neither one does

Neither one tightens loose skin: If sagging is the main complaint, adding volume tends to look heavy rather than lifted. Energy devices or surgery are the honest answer.

Neither one softens a frown line or crow's feet: Those lines come from muscle movement, and botulinum toxin is the treatment that works on muscle.

Neither one is used in the lips: Both carry a higher risk of lumps in lip tissue, and lumps in a product that cannot be dissolved are a poor trade.

Has anyone compared them directly

Not in a way that settles it: Each has been studied on its own, usually against a comparison filler in one area, and the two have not been run against each other in the same face. Clinics that say one clearly beats the other are describing their own experience.

Before you book

Ask which version is being suggested and why that length rather than a shorter one.

Ask how many syringes the plan needs in total, not the price of one.

Ask what happens if you do not like it. For both of these the honest answer is "we wait."

Ask whether the injector has used this product in this area before.

Bring a photo of yourself from a few years ago rather than a photo of someone else.

Related

Questions people ask

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Is Ellanse available in the United States?
No. Ellansé is used in Europe and much of Asia but is not sold in the US, so American readers are usually comparing Sculptra against a different product.
Is Ellanse better than Sculptra?
Neither is better overall. Ellansé gives volume on the day and can be chosen to last up to about three years. Sculptra shows nothing on the day and lasts around two.
Can Ellanse be dissolved?
No. Polycaprolactone has no antidote, so a result you dislike has to be waited out. That wait is longer with the longer-lasting versions.
What do the Ellanse letters mean?
They mark how long the beads take to break down, from roughly a year at the short end to about three years at the long end. Your injector chooses one before treatment.
Do both build collagen?
Yes, both are biostimulators. The difference is that Ellansé also contains a gel that fills straight away, while Sculptra has nothing that fills.
Which is the safer place to start?
Neither, if it is your first injectable. A hyaluronic acid filler can be dissolved, so it is the lower-risk way to learn what you like before committing to something permanent-feeling.