Comparison

Juvederm Ultra vs Ultra Plus

Ultra is the softer gel and the usual lip choice. Ultra Plus is thicker and made for deep folds. Same family, both dissolve, different jobs.
Written & medically reviewed by the Dermapedia team
At a Glance

Juvéderm Ultra is the softer of the two, and it is the usual lip choice. It sits smoothly in soft tissue and gives a natural finish. Juvéderm Ultra Plus is thicker, and it is made for deeper work. It suits the folds running from the nose to the mouth, where a gel has to hold more weight. Both are hyaluronic acid from the same family, and both can be dissolved.

Juvéderm Ultra
Also called Ultra XC, Juvéderm Ultra XC
Juvéderm Ultra Plus
Also called Ultra Plus XC, Juvéderm Ultra Plus XC

How thick the gel is

Medium

Firm enough to shape a lip, soft enough to stay smooth in it.

Thicker

Denser gel with larger particles, so it resists being flattened by the tissue around it.

What it is mainly used for

Lips and the area around them

Lip volume, the lip border, and the lines running out from the mouth.

Deeper folds

The creases from nose to mouth, and other places that need support rather than surface work.

In the lips

The usual pick

It gives volume without feeling hard, which is what most people want from a lip.

Many injectors avoid it

A thicker gel in a lip can feel firm and is more likely to show as a small lump.

How much lift it gives

Moderate

Enough to hold a lip shape. Not enough to prop up a deep fold on its own.

More

It pushes back against tissue, which is what a deep fold needs.

How long it lasts

About a year in a fold, less in a lip
About a year, often a little longer
Both
Thicker gel in a place that moves less tends to last longer. Lips wear filler down faster than anywhere else on the face.

How much is usually used

Often half a syringe to one

Half a syringe is a sensible first lip treatment.

Often one syringe per side

Folds are treated on both sides, so plan for more than one syringe.

Can it be undone

Yes
Yes
Both
Both are hyaluronic acid, so an enzyme called hyaluronidase dissolves either one, usually within a day or two. That is the main reason this family is a sensible first injectable.

What it feels like

Injections, numbed

The XC versions have a numbing agent mixed in, and most clinics use a numbing cream first.

Injections, numbed

Same. A thicker gel takes more pressure to push through the needle, which some people feel more.

Side effects to expect

Bruising, swelling, tenderness

In a lip, too much gel or gel placed too far forward gives a heavy, rolled edge.

Bruising, swelling, firm lumps

Placed too shallow, the thicker gel is more likely to be visible or felt as a ridge.

Both
The serious risk is rare and shared by both: gel entering a blood vessel. Who injects you matters more than which of the two is in the syringe.

Cost

Priced per syringe

Both sit in the same range, so cost rarely decides this.

Priced per syringe

Sometimes a little more, but the difference is small next to how many syringes you need.

Who each suits

Best for
Lips, and soft work around the mouth.
The mindset
You want it to feel natural to the touch.
Best for
Deep folds from nose to mouth.
The mindset
You want support where the face has hollowed.

The whole difference is how dense the gel is

Ultra Plus contains more hyaluronic acid packed into the same volume: That makes it stiffer and slower to spread once it is in place.

Ultra is looser, so it blends into soft tissue more easily: That is exactly what a lip needs and exactly what a deep fold does not.

Neither one is stronger in a useful sense: They are two thicknesses of the same idea, and the area you are treating picks between them.

Why "Plus" does not mean better lips

A lip is soft, thin and always moving: A gel that resists being squashed will sit in it as a firm patch rather than blending in.

Ultra Plus is more likely to be felt as a lump in a lip: It can be dissolved, but nobody enjoys paying twice.

If you want bigger lips, the answer is more gel, not thicker gel: A second half-syringe of Ultra will do more for you than a switch to Ultra Plus.

Where Ultra Plus earns its place

A deep fold from nose to mouth is a structural problem: The tissue above it presses down all day, and a soft gel flattens under that weight.

Ultra Plus holds against it: That is why it is the one reached for when the crease is deep and the skin over it is thick.

Very deep folds sometimes need a firmer gel still: In that case the conversation moves to the thick cheek products rather than to Ultra Plus.

Has anyone compared them directly

No trial has put Ultra against Ultra Plus in the same area: Each was studied on its own, which is standard for fillers.

So the split between them comes from practice, not from a comparison: It is a consistent practice, though, and most injectors follow it.

Before you book

Name the area, not the product. The area decides which of these two is right.

Ask how much gel is planned in total and what that costs.

If you are told Ultra Plus is going in your lips, ask why that gel rather than Ultra.

Book two weeks before anything social. Both bruise, and lips swell hard.

Check the clinic keeps hyaluronidase on site.

Related

Questions people ask

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What is the difference between Juvederm Ultra and Ultra Plus?
Ultra Plus is the thicker of the two. Ultra is softer and is the usual choice for lips, while Ultra Plus is used for deeper folds that need more support.
Is Ultra Plus better for lips?
Usually not. A thicker gel in a lip can feel firm and is more likely to show as a lump. Many injectors will not use Ultra Plus in lips at all.
Which one lasts longer?
Ultra Plus tends to hold a little longer, mostly because it is denser and is used in areas that move less. Both run around a year in a fold.
Can I get bigger lips with Ultra Plus?
More gel gives bigger lips, not thicker gel. A second half-syringe of Ultra will do more than switching product.
Can both be dissolved?
Yes. Both are hyaluronic acid, so an enzyme called hyaluronidase removes either one, usually within a day or two.
Is Ultra Plus more expensive?
Both sit in a similar price range, and both are sold per syringe. How many syringes you need matters far more than which of the two you get.