These two are closely related — closer than most comparisons on this site. When Sciton took its 1927 nm laser to the FDA, the device it was compared against to win clearance was Fraxel.
The practical difference is depth. Moxi runs at 1927 nm, absorbed by water very near the surface, so it works in and just under the epidermis. Fraxel Dual offers that same 1927 nm setting and a 1550 nm setting that reaches deeper into the skin.
So Fraxel can do more, and asks more of you. Moxi is the gentler, quicker-recovery option. Fraxel at its deeper setting does more for texture and scarring, with more downtime.
One wavelength: 1927 nm.
1927 nm for surface pigment, 1550 nm for deeper work.
Because Fraxel has two settings, "Moxi or Fraxel?" is often the wrong question. The better one is: which wavelength, and why?
Moxi's FDA clearance covers soft tissue coagulation, actinic keratosis and benign pigmented spots — lentigines, solar lentigines and freckles. Wrinkles, texture and melasma are not in it.
Fraxel is different here. Its 1550 nm clearance names melasma, actinic keratosis, periorbital wrinkles, acne scars and surgical scars.
Providers treat off-label all the time, which is legal and routine. But if a clinic cites FDA clearance for melasma, it is worth asking which device and which wavelength — because for one of these two the answer is real and for the other it is not.
If you get cold sores, tell your provider. Either laser can reactivate the virus, and the standard precaution is antiviral medication started in advance.