Comparison

Neveskin vs CoolSculpting

No FDA clearance could be found for Neveskin under that name, and no published study of it. CoolSculpting holds a 2010 De Novo plus a chain of 510(k)s. Here is how to run the regulatory check yourself.
Written & medically reviewed by the Dermapedia team
At a Glance

No FDA clearance for Neveskin could be found, and it is worth being exact about what that sentence means. A search of the FDA's 510(k) database by device name returns nothing under that name. A search of the FDA device registration and listing database by proprietary name returns nothing either. No published clinical study of Neveskin could be found. That is what those searches return. It is not a finding by the FDA about the product.

CoolSculpting sits at the other end of the paper trail. It holds a De Novo authorisation from 24 August 2010 that created the FDA category for cryolipolysis. More than a dozen 510(k) clearances have followed. Each one adds a named body area, with its own indication wording and its own reviewed evidence.

None of that makes one treatment good and the other bad. Clearance is not proof a device works. The 510(k) route only establishes that a device is much the same as something already on the market. And treatments are lawfully offered outside cleared indications all the time, because the FDA regulates what manufacturers claim, not the practice of medicine.

What a missing clearance does change is what you can look up before you pay. With a cleared device, there is a public document. It tells you, in the FDA's own words, what the device is cleared to treat, in which body areas, and in whom. Without one, there is nothing to check against. So the most useful thing here is a walkthrough of how to run that check yourself.

Neveskin
marketed as a body-contouring treatment; no FDA clearance found under that name
CoolSculpting
Zeltiq/Allergan, cryolipolysis, fat freezing

What it is

Sold as a body-contouring treatment through clinics and med-spas

No maker's technical description could be obtained from a primary source. So this page will not describe how it works. A clinic offering it should be able to name the maker and the model.

A cooling applicator that draws a fold of tissue against chilled plates and holds it there for a set cycle

It was authorised under De Novo request DEN090002, decided 24 August 2010. Every body area added since has come through a separate 510(k). That is a finding that a device is much the same as an earlier one, not proof of benefit.

How it works

Not established from a primary source
Cold, pulled out of the fat through the skin, injuring fat cells so the body clears them over weeks

Fat cells are more easily harmed by cold than skin, nerve and vessel. The cleared treatment settings are specific: minus 10 degrees Celsius for 60 minutes under the chin, and minus 11 degrees for 35 minutes on the upper arm.

What it is cleared to treat

No FDA clearance was found under the name Neveskin, so there is no cleared indication to quote

Scope that carefully. The FDA 510(k) database returns no match on that device name. The registration and listing database returns no match on that proprietary name. Devices are sometimes cleared under a maker's model number rather than the trade name a clinic uses. So a clearance may exist under a name nobody advertises.

Cold-assisted lipolysis, meaning breakdown of fat, of the upper arm, bra fat, back fat, banana roll, thigh, abdomen and flank, in people with a body mass index of 30 or less

The submental and submandibular areas are cleared separately, up to a body mass index of 46.2. CoolSculpting Elite is K212707, cleared 5 November 2021.

What has been published about it

No clinical study of Neveskin could be found in the published literature

Again, that is the outcome of a search. It is not proof that none exists.

A large but uneven literature, much of it manufacturer-linked

The FDA's own pooled review in K160259 covered 4,792 treatment cycles. It accepted a mean fat-layer reduction of about 20% by ultrasound. An independent randomised split-body trial in 2023 measured about 14%. A 2022 systematic review found that only 5 of 381 screened articles survived a formal check for bias.

What the numbers actually describe

Nothing published to describe
Thickness of the fat layer at one measuring point, and whether blinded reviewers can pick out the "before" photograph

Blinded photo picking is the main endpoint in most of these clearances. In the pivotal under-chin study, run by the manufacturer, reviewers were 91% correct, against a pre-set bar of 80%. That is a spot-the-difference test, not a measurement of how much fat went.

Downtime

Not established from a primary source
Little to see, but the area is numb, red and firm for days to weeks

Delayed pain arriving several days later is common. A review of 554 procedures found it ran 3 to 11 days and settled on its own.

Sessions

Not established from a primary source
Median 4 cycles across 1 session, in a real-world review of 3,262 patients and 18,203 cycles

The mean was 5.6 cycles and 1.9 sessions. Results in the FDA-reviewed trials were checked at 12 or 16 weeks.

Cost

No dated national figure has been published
Self-reported by 1,928 RealSelf reviewers as an average of $3,268, range $750 to $8,800, page last updated 10 April 2024

Those reviewers rated it 59% "Worth It". The American Society of Plastic Surgeons' last published average physician fee for non-surgical fat reduction was $1,157, for 2023. That figure is a category average across six unrelated products, not a CoolSculpting price. The 2024 report published no minimally invasive fees at all.

Who tends to be happy with it

Best for
Someone who has asked the clinic for the maker and model, checked it themselves, and is comfortable with what they found.
The mindset
Going in knowing there is no public document setting out what the device is cleared to do.
Best for
Someone near a stable weight with a defined bulge that will not shift, in one of the named cleared areas.
The mindset
One area, volume only, measured in millimetres over about three months.

How to check a device's regulatory status yourself

This takes about five minutes, and it is the same check anyone would run.

Start by asking the clinic for two things: the maker's name, and the model or device name on the machine: Not the treatment name on the price list. Devices are routinely cleared under a maker's model number and then sold under a completely different trade name. So searching the brand you were quoted can come up empty even when a clearance exists. This is normal, not suspicious.

Then search the FDA's 510(k) database at accessdata.fda.gov: You can search on device name and, more usefully, on applicant, meaning the company that filed. Searching by company name catches devices whose trade name never appears in the FDA record. If you find a match, open the clearance document and read the page headed "Indications for Use". That page is the only place the cleared wording lives, and it is often narrower than the marketing.

Search the FDA's registration and listing database too: A company that imports or distributes a device in the US is meant to register and list it. A listing is not a clearance. But its absence, alongside an absent clearance, tells you the search was thorough.

Read the indication as a sentence, not a headline: The wording will name the effect: "lipolysis", "reduction in circumference", "temporary reduction in the appearance of cellulite". It often names the body areas. Sometimes it sets a body mass index limit, and sometimes it includes the word "temporary". All of that is meaningful, and none of it has to appear in an advertisement.

What "no clearance found" does and does not mean

It does not mean the FDA looked at the device and rejected it. It does not mean the device is unsafe. It does not mean a clinic offering it is doing anything wrong. Plenty of legitimate, well-run businesses use devices this way. Using a device outside or without a US clearance is a question for the maker and the regulator. It is not an accusation against a practitioner.

It also does not mean no clearance exists. A search under the name "Neveskin" returns nothing. A device sold under that name could still be cleared under a maker's model number, or under a company name that never appears in the clinic's material. Re-running the search under the name printed on the machine is the step that settles it.

What it does mean is narrower and more practical. There is no public FDA document stating what this device is cleared to do, in which areas, or in whom. So there is nothing to compare a claim against, and no reviewed evidence sitting behind the wording. With CoolSculpting you can read that the clearance covers seven body regions at a body mass index of 30 or less, plus two more under the chin up to 46.2. You can then judge whether what you are being offered fits inside it.

Questions worth asking at the consultation

What is the maker's name and the model name on the device?

Does it hold an FDA clearance, and if so, for what wording?

Is what you are proposing for me inside that wording, or outside it?

What has been measured and published for this device - not for the technology in general, for this device?

How many sessions, over how long, and what does the total cost come to?

Off-clearance treatment is legal and common. The point of asking is not to catch anyone out. It is that when a treatment sits outside a cleared indication, the evidence the FDA reviewed does not cover what is being done to you. Neither does the maker's safety data. You are entitled to know that in advance.

Neither of these will change what you weigh

The FDA's own body-contouring page, last updated 15 October 2025, states that non-invasive body contouring "does not treat obesity or improve your health. It will not result in weight loss." CoolSculpting's maker safety document says the same in its own words. The body mass index figures inside the clearance are limits on who may be treated. They are not something the treatment is meant to move. No professional society has published a formal position statement on this. The regulator and the maker are the sources.

Before you book

If cold is involved in any way, disclose cryoglobulinemia, cold agglutinin disease or paroxysmal cold hemoglobinuria: These three are the absolute bars on CoolSculpting's own safety document. They share one logic: blood that reacts badly to cold.

Mention any hernia at or near the area, including a repaired one: Hernia appears in the FDA's class-wide risk list and in the CoolSculpting precautions. It is the item most often skipped.

Ask, in advance, what happens if something goes wrong: With a cleared device there is a maker, a safety document, and a route for reporting an adverse event to the FDA. Where the device could not be found in the FDA's databases, ask who supports the machine and who you would contact.

Also disclose: cold urticaria, Raynaud's or chilblains, reduced feeling or blood flow in the area, bleeding disorders or blood thinners, recent surgery or scarring at the site, active implanted devices such as a pacemaker, and eczema or dermatitis over the treatment area.

Get emergency help now

Fever or chills after treatment

Redness spreading outward from the treated area hour by hour

Pus or discharge from treated skin

These suggest spreading infection and need urgent care the same day.

Call your provider if

A firm, well-defined lump appears in a CoolSculpting-treated area two to six months later, above all if it matches the shape of the applicator. This is paradoxical adipose hyperplasia. It does not go away by itself, and further cryolipolysis to the same area has been reported to worsen it

Pain or swelling is getting worse after day three instead of settling

Numbness in the area is still there past about three months

Blistering, crusting or an open area appears

The skin over the treated area darkens over the following weeks

The area looks hollow or dented next to the other side

Questions people ask

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Is Neveskin FDA cleared?No clearance could be found under that name. A search of the FDA's 510(k) database by device name and of the FDA device registration and listing database by proprietary name both returned nothing. That is the result of those searches, not a decision by the FDA. Devices are often cleared under a manufacturer's model number rather than the name a clinic advertises, so the search worth running is the one using the manufacturer and model printed on the machine.
Does that mean it is unsafe or that the clinic is doing something wrong?No. Plenty of legitimate businesses run devices this way, and treating outside or without a US clearance is a matter between the manufacturer and the regulator rather than a mark against a practitioner. What it does mean is that there is no public document setting out what the device is indicated to do, so there is nothing to check a claim against.
How do I check a device's FDA status myself?Ask the clinic for the manufacturer and the model name, then search the FDA's 510(k) database at accessdata.fda.gov by applicant as well as by device name. If you get a match, open the document and read the page headed "Indications for Use" — that is where the cleared wording lives. The FDA registration and listing database is a useful second check.
Does an FDA clearance mean a device works?Not on its own. A 510(k) clearance is a finding that the device is substantially equivalent to one already legally on sale. Clinical data is sometimes required and sometimes not. It is a statement about similarity, not about how well something works or whether it is worth the money.
Is there any published research on Neveskin?None could be found. A search of the published literature under that device name returned no clinical study. As with the clearance search, that is an absence of found evidence rather than proof that nothing exists.
What does CoolSculpting have that is different?A paper trail you can read. A De Novo authorisation from 24 August 2010 created the category, and more than a dozen 510(k) clearances since have each added a named body area with its own wording. That still is not proof of benefit, and the primary endpoint in most of those clearances was whether blinded reviewers could pick out the "before" photograph — a detection test, not a measurement of fat.
How much fat does CoolSculpting actually remove?The FDA's own pooled review accepted a mean reduction of about 20% by ultrasound across 4,792 treatment cycles, with individual studies ranging from 10.3% to 25.5%. An independent randomised trial in 2023 measured about 14%. All of those describe the thickness of the pinched fat layer at one point — not body fat, not weight, and not the volume of the bulge.