Comparison

Opus Plasma vs Microneedling

Opus Plasma is a plasma resurfacing device - no needles, nothing enters the skin - cleared only for ablation and resurfacing. Microneedling makes physical channels without heat and names facial acne scars in its authorisation.
Written & medically reviewed by the Dermapedia team
At a Glance

Opus Plasma is not radiofrequency microneedling, even though clinics often list it next to Morpheus8. It has no needles, and nothing goes into the skin. Radiofrequency energy at the tip creates micro-plasma, which arcs to the skin surface and makes tiny controlled ablation perforations with a zone of heat beneath them. Mechanically it sits closer to a fractional laser than to any needle device.

Microneedling is the opposite trade. Fine needles physically enter the skin and make thousands of channels, with no energy and no heat at all. The wound and the healing response are the whole treatment.

Read the two clearances precisely, because they say quite different things. Opus was cleared as K201520 on 27 October 2021 to Alma Lasers. The Plasma tips, Focus and Glide, used with the unipolar applicator - unipolar meaning the current travels out from the tip through the tissue rather than between a pair of electrodes inside it - are "indicated for dermatological procedures requiring ablation and resurfacing of the skin"; the Colibri tips are indicated for "resurfacing of the skin" only. Wrinkles, acne scars, laxity, tightening and pigment appear in neither, and the clearance carries no skin-type statement. Microneedling's authorisations, by contrast, name facial acne scars outright.

The evidence is lopsided too. No Opus Plasma-specific peer-reviewed trial was found in the published literature. Microneedling for acne scars has a pooled analysis of 24 randomised trials behind it.

Opus Plasma
Alma Lasers, plasma resurfacing
Microneedling
fine needles, no energy

What it is

A fractional ablative resurfacing device - radiofrequency at the tip creates micro-plasma

It shares an FDA product code with radiofrequency microneedling devices, which is one reason the two get grouped together.

A motorised pen driving fine needles into the skin

No energy is involved at any point.

How it works

Plasma arcs from the tip to the skin surface, making micro-perforations with a zone of heat under each one

Nothing penetrates. The tips do not enter the skin.

The needles enter the skin; healing does the rest
Both
This is the distinction that matters. One removes tiny points of surface skin with heat; the other makes channels through it without heat.

How deep it goes

Not established - depth of effect is not specified in the retrievable FDA summary

Pin counts and operating frequency are not stated there either, so none are quoted here.

Set by the pen and the operator. SkinPen is adjustable from 0 to 2.5 mm; Dermapen 4 from 0.2 to 3.0 mm

What it is cleared to treat

Ablation and resurfacing of the skin, on the Focus and Glide plasma tips; resurfacing only on the Colibri tips - K201520, 27 October 2021

Wrinkles, acne scars, laxity, tightening and pigment are not named in it, and no skin type is specified.

Facial acne scars, plus wrinkles of the neck in Fitzpatrick skin types II to IV for SkinPen

DEN160029 (2018) and K202243 (2021) for SkinPen; K221070 (2022) for Dermapen 4, facial acne scars in Fitzpatrick I to V.

Both
Clearance is a finding of similarity to an earlier authorised device, not proof of benefit. Treating outside the cleared words is legal and routine - it is just worth knowing when it is happening.

Published evidence

None specific to it - no Opus Plasma trial was found in the published literature

Where clinics cite "studies", they are usually studies of other devices.

A review pooling 24 randomised trials and 1,546 people for acne scars, ranking the treatments against each other

Microneedling combined with another treatment outperformed microneedling alone; microneedling with a chemical peel ranked best.

Downtime

Not established - no published study reports a recovery time for it

It is a fractional ablative treatment, so tiny points of surface skin are removed and marks are expected. Ask your provider for their own expected timeline in writing rather than accepting a general claim.

Redness like a moderate sunburn for roughly 24 to 72 hours, with mild swelling and occasional pinpoint bleeding on the day

Conventional clinical description, not a labelled figure.

Who tends to be happy with it

Best for
Someone whose provider is treating surface texture and is willing to explain what the device is cleared for and what recovery to expect.
The mindset
Understand you are having an ablative resurfacing treatment, not a needling one, and ask for a test area.
Best for
Acne scarring and texture, over a course, with no heat involved.
The mindset
Small controlled injuries, modest gains, judged at around three months.

The pigment question, stated honestly

There is no published pigmentary safety data for Opus Plasma, and its clearance names no skin type at all. What can be said is structural rather than measured: Opus removes tiny points of surface skin using heat, while microneedling makes channels without heat. Heat and injury at the surface are what drive pigment problems after resurfacing treatments in general, so the two mechanisms would not be expected to behave the same way.

Nobody has measured how that plays out for Opus specifically. If you have a deeper skin tone, that is a reason to ask for a test area first, to ask what settings are planned, and to ask the provider how many people with your skin tone they have treated with this device.

What each one cannot do

Opus does not needle. Nothing is inserted, so it does not deposit heat at a chosen depth in the dermis the way radiofrequency microneedling does. It is a surface treatment.

Microneedling does not tighten loose skin meaningfully and does not reach or heat the fat underneath, so it changes texture rather than shape.

Neither is a substitute for the other, and no published study compares them.

Before you book

If you get cold sores, tell your provider when you book, not on the day. Antiviral medicine is started in advance, so it has to be prescribed beforehand. Reactivation is well documented after laser resurfacing, which is where this precaution comes from.

Disclose a pacemaker or implantable defibrillator, and any metal implant near the treatment area, before any radiofrequency-based treatment. Opus generates its plasma with radiofrequency energy. These are labelled contraindications for radiofrequency devices, precautionary rather than tested, and your cardiology team is the right source of advice.

Any active infection in the area is a reason to postpone. Ask for a test area if you have a deeper skin tone, and, for microneedling, ask whether the cartridge is sterile and single-use.

Get emergency help now

  • A fever, redness spreading outward from the treated area, or pus - these can mean a spreading infection

Call your provider if

  • Redness, swelling or pain is increasing after day three instead of settling
  • Blistering, crusting or an open area appears, or crusting lasts longer than you were told to expect
  • The treated skin darkens noticeably over the following weeks
  • A pattern of marks is still visible well beyond the recovery time you were given
  • A cluster of small painful blisters appears - this can be a cold sore flare

Related

Questions people ask+
Is Opus Plasma the same as RF microneedling?No. It uses radiofrequency energy, but to create plasma at the skin surface rather than to heat the dermis through needles. There are no needles and nothing penetrates the skin. Clinics list the two together because they share an FDA product code, not because they work the same way.
Which one has more downtime?Microneedling's recovery is well described - redness like a moderate sunburn for roughly 24 to 72 hours. For Opus Plasma, no published study reports a recovery time, so none is quoted here. It is an ablative treatment, meaning tiny points of surface skin are removed, so ask your provider for their own expected timeline in writing.
Which is better for acne scars?Microneedling is the one with matching paperwork and pooled evidence: facial acne scars are named in its authorisations, and a review that pooled 24 randomised trials and ranked the treatments against each other supports it. Opus Plasma's clearance does not name acne scars, and no trial of it was found in the published literature.
Is Opus Plasma FDA cleared?Yes, as K201520 on 27 October 2021 - for ablation and resurfacing of the skin on its plasma tips, and resurfacing only on its Colibri tips. It is not cleared for wrinkles, acne scars, laxity or pigment. Clearance also means the device was found similar to an earlier one, not that a benefit was proven.
Is it safe for darker skin?There is no published data either way, and the clearance names no skin type. Ask for a test area, ask what settings are planned, and ask how many people with your skin tone the provider has treated with the device.
Does Opus Plasma tighten skin?Tightening is not in its cleared wording, and no published trial of the device was found. Any tightening claim you are shown is either clinic experience or evidence generated on a different machine - it is fair to ask which.
Can I have both?No published study has combined or compared them, so there is no evidence on sequencing or spacing. If both are proposed, ask why, in what order, and how long apart.