The "non-comedogenic" label is not reliable. It is an unregulated marketing term in the US. There is no legal definition, no required test, and no standard a product must meet to print it. Any brand can use it on anything.
This cream is badged non-comedogenic while containing myristyl myristate, which scores the maximum on the old comedogenicity scale. That sounds alarming, but those old ratings were mostly generated on rabbit ears and translate poorly to human faces. So the ingredient is not proof it will clog you either.
The takeaway is simple: the label is not evidence, in either direction. If you are acne-prone and this breaks you out, trust your skin. For most people, it is a genuinely well-built daily moisturizer.
| Key active | Ceramide-3 + niacinamide + glycerin |
| Texture | Lightweight cream |
| Best for | Normal to dry skin; sensitive skin; daily use |
| Approximate price | $20–25 |
| Fragrance | Fragrance free |
This is a genuinely well-built daily moisturizer, and it is the one many dermatologists reach for when someone wants a single, uncomplicated face cream.
Fragrance-free, with ceramide-3, niacinamide and glycerin — three ingredients with real supporting evidence between them.
About $7 an ounce for 100 ml, which is good value for the quality of the formula.
The texture is genuinely versatile — light enough for combination skin, rich enough for dry.
It is labeled "non-comedogenic" and contains myristyl myristate, which scores 5 out of 5 — the maximum — on the old comedogenicity scale. It also contains glyceryl stearate SE and myristic acid, both rated 3.
Here is the thing that matters more: "non-comedogenic" is an unregulated marketing term. There is no legal definition in the US, no required test, and no standard a product has to meet to print it on the box. Any brand can use it on anything.
That does not mean this cream will clog you — the old comedogenicity ratings were mostly generated on rabbit ears and translate poorly to human faces. It means the label is not evidence. If you are acne-prone and this breaks you out, believe your skin over the box.
The marketing still sells "Prebiotic Thermal Water," but the current ingredient list just says water. The parenthetical was dropped.
The foundational thermal-water research is authored by a La Roche-Posay scientist.
Do not confuse it with the SPF 30 or Matte versions — different products, different formulas.
Water, Glycerin, Squalane, Dimethicone, Zea Mays Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Stearic Acid, Ceramide NP, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Capryloyl Glycine, Caprylyl Glycol, Xanthan Gum
1. Niacinamide-containing facial moisturizer improves skin barrier and benefits subjects with rosacea (https://pubmed.ncbi.nlm.nih.gov/16209160/) — Backs the claim that niacinamide has real supporting evidence: a randomized study (Cutis 2005) showed a niacinamide-containing moisturizer measurably improves stratum corneum barrier function and reduces dryness. 2. The Efficacy of Moisturisers Containing Ceramide Compared with Other Moisturisers in the Management of Atopic Dermatitis: A Systematic Literature Review and Meta-Analysis (https://pmc.ncbi.nlm.nih.gov/articles/PMC10162745/) — Backs the claim that ceramide (ceramide-3/ceramide NP) has real supporting evidence: this meta-analysis (Indian J Dermatol 2023) found ceramide-containing moisturizers improve disease severity (SCORAD) and TEWL/barrier measures. 3. Glycerol as a Skin Barrier Influencing Humectant (https://link.springer.com/chapter/10.1007/978-3-642-27606-4_32) — Backs the claim that glycerin has real supporting evidence: this book chapter documents glycerol acting as a humectant that increases stratum corneum hydration and speeds skin-barrier reconstitution after damage. 4. La Roche-Posay Toleriane Double Repair Moisturizer ingredients (Explained) — INCIDecoder (https://incidecoder.com/products/la-roche-posay-toleriane-double-repair) — Confirms the product formulation facts: it is fragrance-free and contains Glycerin, Niacinamide, Ceramide NP (ceramide-3), Myristyl Myristate, Glyceryl Stearate SE and Myristic Acid. 5. Myristyl Myristate (Explained + Products) — INCIDecoder (https://incidecoder.com/ingredients/myristyl-myristate) — Confirms the claim that myristyl myristate scores 5 out of 5 (the maximum) on the comedogenicity scale and may clog pores.