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how many units of xeomin for forehead

Written & medically reviewed by the Dermapedia team
At a Glance

The approved dose is 20 units, given as five injections of 4 units each across the forehead muscle.

Only two brands have an FDA-approved forehead dose, and the numbers are identical. Botox Cosmetic has had the forehead indication since 2017; Xeomin's was added in July 2024. Both are 20 units. For Dysport, Jeuveau, Daxxify and Letybo, forehead treatment is off-label and no reviewed dose exists.

One condition attached to it: the label approves the forehead dose only when the frown lines between the brows are treated in the same session. That brings a combined visit to 40 units.

Key Facts

Approved forehead dose20 units, in 5 injections of 4 units
The label also directsTreat the forehead together with the frown lines, to reduce the risk of heavy brows
Frown-line dose20 units, in 5 injections of 4 units
Forehead plus frown lines40 units
Crow's feet, if added24 units — 4 units at 3 points per side
Maximum for all three upper-face areas64 units in one session
Placement rule on the labelAt least 2 cm above the bony eye socket rim
RetreatmentNo sooner than every 3 months

The approved dose

Most questions about forehead dosing have no official answer, because the forehead is off-label for most botulinum toxin products. Xeomin is one of two exceptions — Botox Cosmetic is the other — so this one has a real number behind it.

20 units, in five equal injections of 4 units, into the frontalis — the flat sheet of muscle across your forehead that lifts your brows.

The label adds a placement rule: injections should be at least 2 cm above the bony rim of the eye socket. That distance is the safety margin for your brow position.

Why it comes with the frown lines attached

The label directs that the forehead be treated in conjunction with the frown lines, and it says why: to reduce the chance of the brows dropping.

Your forehead muscle is the only one that lifts your brows. The muscles between your brows pull them down. Relax the lifter on its own and the downward pull is unopposed, which can leave the brow sitting lower than before. Treating both keeps the two forces in balance.

So a realistic forehead appointment is 40 units: 20 in the forehead, 20 in the frown lines.

Adding crow's feet

If you are also treating the lines at the outer corners of the eyes, the label dose is 24 units — 4 units at three points on each side.

Everything together — frown lines, forehead, crow's feet — is capped at 64 units in a single session.

Why 20 units and not more

It is tempting to think a stronger forehead needs a bigger dose. The label does not offer one, and there is a good reason to be careful rather than generous here.

Over-treating the frontalis is what produces heavy brows and hooded lids. That is usually a cosmetic problem rather than a medical one, it lasts for months, and there is nothing to be done except wait — but if the heaviness is enough to get in the way of your vision, or if an upper eyelid itself is drooping, that should be looked at rather than waited out. Injectors generally prefer to start at the approved dose, review at two weeks, and add units if the result is lighter than you wanted.

Adding is easy. Removing is impossible.

A note on comparing brands

If you have had Dysport or Botox in your forehead, do not carry the unit number across. Every one of these labels states that its units cannot be converted into another brand's.

20 units of Xeomin in the forehead is not a smaller treatment than 50 units of Dysport somewhere else. They are different scales.

Get emergency help now if

  • You have trouble swallowing, speaking, or breathing
  • You feel weakness spreading to muscles you did not have treated

Go to an emergency department or call 911. Do not wait for a call back. These are rare, but they are the symptoms named in the FDA boxed warning that every botulinum toxin product carries, deaths have been reported, and they can begin hours or even weeks after treatment.

Call your injector if

  • One eyelid or eyebrow starts to droop, or your vision changes
  • One side sits noticeably higher than the other at two weeks

If a vision change is sudden or severe, seek urgent care rather than waiting.

  • Your brows feel heavy enough to get in the way of your sight
Questions people ask+
How many units of Xeomin for the forehead?20 units, given as five injections of 4 units. This is the FDA-approved dose, and it applies when the frown lines are treated in the same session.
How many units of Xeomin for the forehead and frown lines together?40 units — 20 in each area.
Why does the label say to treat the frown lines too?To reduce the chance of the brows dropping. The forehead muscle is the only one that lifts your brows, and the muscles between the brows pull them down. Treating only the lifter can leave the brow sitting lower. Treating both keeps them balanced.
What is the maximum Xeomin dose for the upper face?64 units in one session, covering frown lines (20), forehead (20) and crow's feet (24).
Is Xeomin the only toxin approved for forehead lines?No. Botox Cosmetic has been approved for forehead lines since 2017 and Xeomin since July 2024, both at 20 units. Dysport, Jeuveau, Daxxify and Letybo are approved for frown lines only in the US.
Can I have more than 20 units in my forehead?That would be above the approved dose. Injectors do exceed label doses in practice, but over-treating the forehead is what causes heavy brows, and it cannot be reversed. Discuss it before rather than after.
How soon can I have it again?No more often than every three months.
References+
FDA prescribing information for Xeomin (incobotulinumtoxinA)
Source for the 20-unit forehead dose in five 4-unit injections, the requirement that it be given with glabellar treatment, the 24-unit lateral canthal dose, the 64-unit upper-face maximum, the 2 cm placement rule, the three-month retreatment interval, and the statement that units are not interchangeable with other products.
FDA approval letter, BLA 125360 supplement S-099, 5 July 2024
The approval adding horizontal forehead lines and lateral canthal lines to Xeomin's cosmetic indication.
FDA prescribing information for Botox Cosmetic (onabotulinumtoxinA)
Source for the 2017 forehead line indication, the matching 20-unit forehead dose, and the same 64-unit combined upper-face maximum.
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