Comparison

Innotox vs Botox

Innotox is a Korean botulinum toxin sold as a ready-mixed liquid. Botox is mixed from powder and approved in the US. What the difference actually means.
Written & medically reviewed by the Dermapedia team
At a Glance

Innotox is a botulinum toxin made in South Korea and sold as a ready-mixed liquid. It was the first toxin sold that way, so the clinic does not mix a powder with saline before injecting. Botox is the original brand, sold as a powder, and it is approved for use in the United States. Innotox is not approved here, it cannot legally be sold or imported for use in the US, and no trial has compared the two.

Innotox
Also called Medytox, liquid botulinum toxin type A
Botox
Also called Botox Cosmetic, onabotulinumtoxinA

What it is

A botulinum toxin type A from Korea

Made by Medytox and approved in South Korea. It is the first version of this drug sold as a ready-to-use liquid.

The original botulinum toxin brand

The version most American clinics stock, and the one most of the published research used.

What form it comes in

Liquid, already mixed

It goes straight from the vial to the syringe. Nothing is added at the clinic.

Powder, mixed with saline on site

The clinic decides how much saline to add, which sets how dilute the injection is.

Where you can get it

Korea, and parts of Europe and elsewhere

It has never been approved in the United States, and bringing it in to inject is not legal here.

Widely, across the United States

It is a prescription drug, so it is injected by a licensed practitioner.

What it is used for

Lines that appear when you move

The same targets: frown lines between the brows, forehead lines, crow's feet.

Lines that appear when you move

It is approved in the US for specific facial movement lines. Other uses are common and are off-label.

Both
Neither one softens a line that is there when your face is completely still. That line is skin damage or lost volume, and it needs a different treatment.

How long until it works

A few days

Reported onset is much the same as other toxins.

Three to four days, fully by two weeks

Judge the result at two weeks, not at day three.

How long it lasts

About three to four months

That is the reported range. No trial has compared it with Botox to see whether it lasts longer or shorter.

About three to four months

It fades gradually. Movement comes back before the line does.

The downside

You cannot check where a vial came from

Vials sold online have no traceable path from the factory to your face. Nobody can confirm how they were stored or that the contents match the label.

The usual toxin trade-offs

Bruising and headache are common for a few days. If the toxin spreads slightly beyond the target, a brow or eyelid can droop for weeks until it wears off.

Cost

Cheaper abroad, per vial

Price is the main reason people ask about it.

Priced per unit or per area

Ask which of the two your clinic uses, because the totals are not comparable.

The at-home or drugstore version

There is none

This is an injected prescription drug. There is no version of it you can apply.

Peptide serums borrow the name

"Botox in a bottle" creams sit on the surface. The muscle they claim to relax is several millimetres down, and a cream does not reach it.

Who each suits

Best for
Someone being treated in a country where Innotox is approved and supplied through a clinic.
The mindset
A convenience difference in how the drug is packaged, not a different result.
Best for
Anyone being treated in the United States.
The mindset
The version with the longest track record and a supply chain you can check.

Liquid versus powder, and what it actually changes

A ready-mixed liquid removes one step from the clinic's routine: Powdered toxin has to be mixed with saline before use, and the person doing it chooses how much saline to add.

That step is where some of the variation between clinics comes from: A more dilute mix spreads further under the skin. A stronger mix stays tighter to the injection point.

For you, the effect of the difference is small: A careful injector gets consistent results from powder. The convenience belongs to the clinic more than to the patient.

Why "same active ingredient" is not the whole answer

All of these products are botulinum toxin type A, and they are not interchangeable: Each brand is made by a different process, with different proteins around the toxin, and each has its own unit strength.

A unit of one brand is not a unit of another: A dose that suits one product can be too much or too little of a different one, so an injector has to know which product is in the syringe.

That is the practical reason brands matter here: It is not marketing. It is dosing.

What buying a toxin online means in practice

Vials sold to consumers online sit outside any system that can be checked: Botulinum toxin is a prescription drug, and the route from a factory in one country to a website to a doorstep leaves no record anyone can verify.

Three things become unknowable: Whether the vial contains what the label says. Whether it was kept cold the whole way. Whether there is anyone to contact if a batch is recalled.

Injecting it is also a medical act, wherever the vial came from: The dose, the depth and the exact muscle all decide whether the result looks natural or leaves a brow sitting oddly for two months.

Has anyone compared them directly

No published trial has put Innotox against Botox: Claims that one lasts longer or looks more natural come from clinic experience and from marketing, not from a head-to-head study.

Before you book

Ask which product is being used, and ask to see the vial.

Ask whether you are being charged per unit or per area, and get the total before you agree.

Book a review at two weeks. That is when the result is settled and a small top-up can be added.

Tell your injector about any previous toxin treatment, including anything you had abroad.

Related

Questions people ask

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Is Innotox the same as Botox?
They are both botulinum toxin type A, but they are different products from different makers. Innotox comes ready-mixed as a liquid; Botox comes as a powder the clinic mixes with saline.
Is Innotox approved in the US?
No. Innotox has never been approved in the United States, and selling or importing it for use here is not legal. It is approved in South Korea and sold in several other countries.
Does Innotox last longer than Botox?
There is no evidence either way. No trial has compared them, and reported duration for both sits in the same three to four month range.
Why is Innotox cheaper?
It is priced for markets outside the United States, and vials sold online skip the licensed supply chain entirely. That price gap is the main reason people ask about it.
What is the risk of buying botulinum toxin online?
There is no way to confirm that the vial holds what the label says, that it was kept cold, or that anyone would reach you if a batch were recalled. Nobody can check the path it took.
Do Innotox and Botox use the same units?
No. Each brand has its own unit strength, so a dose of one does not translate to a dose of another. That is why the injector needs to know which product is in the syringe.