Comparison

Radiesse vs Voluma

Voluma is a reversible hyaluronic acid gel for cheek volume. Radiesse builds collagen and suits jaw and chin, but cannot be dissolved.
Written & medically reviewed by the Dermapedia team
At a Glance

Voluma is the better choice for cheek volume, and for anyone who wants a way out. It is a firm hyaluronic acid gel that lifts the mid-face the same day and can be dissolved. Radiesse is the better choice for a defined jawline, chin or the backs of the hands. It gives volume on the day and then builds collagen, but it cannot be dissolved. If this is your first injectable, that difference should weigh heavily.

Radiesse
Also called calcium hydroxylapatite, CaHA, collagen stimulator
Juvéderm Voluma
Also called Voluma XC, hyaluronic acid filler, cheek filler

What is in the syringe

Calcium microspheres in a gel

Calcium hydroxylapatite is the same mineral found in bone. The gel carrier fades and the collagen it triggers takes over.

Hyaluronic acid gel

A firmly cross-linked gel. Hyaluronic acid is a sugar your skin already makes.

What it is used for

Structure and edges

Jawline, chin, temples and the backs of the hands. It is stiff, so it holds a defined line.

Cheek volume

The mid-face. It is designed to sit deep over the cheekbone and lift the tissue above it.

What happens over time

Volume now, then a dip, then a build

Fuller straight away, a little less full at around two months, then better again as collagen forms.

Steady, then a slow fade

What you see at two weeks is roughly what you keep until it wears off.

How long it lasts

About a year

Some of the collagen benefit outlives the product itself.

Up to about two years

One of the longer-lasting hyaluronic acid gels, because the cheek moves little.

Can it be undone

No

There is no enzyme for calcium hydroxylapatite. A result you dislike has to be waited out.

Yes

Hyaluronidase dissolves it, usually within a day or two.

Where it should not go

Not the lips

Radiesse has a higher rate of lumps in lip tissue, so it is not used there.

Not usually the fine lines

Voluma is too firm for lips and lip lines. Softer products in the same family are used there.

Side effects to expect

Bruising, swelling, firmness

Small lumps are the specific complaint, and they cannot be dissolved away.

Bruising, swelling, tenderness

Lumps and unevenness happen, but they can be dissolved.

Both
The serious risk is rare and shared by both: product entering a blood vessel. Who injects you matters more than which product they use.

Cost

Priced per syringe

Often fewer syringes are needed for a jawline than people expect.

Priced per syringe

Cheek work commonly uses one syringe per side, so budget for two.

The at-home or drugstore version

There is not one

No cream carries calcium microspheres under the skin, and no collagen drink builds collagen in one chosen spot.

A hyaluronic acid serum

A serum holds water in the top layer for a few hours. Voluma is placed on the bone. Same molecule, different depth, different job.

Who each suits

Best for
Jaw and chin definition, and thin-looking hands.
The mindset
You want an edge, and you accept it cannot be undone.
Best for
Flat or hollow cheeks.
The mindset
You want lift today, with the option to reverse it.

They are two different kinds of product

Voluma is a filler and nothing more: It takes up space where volume is missing and holds that space until your body clears it. What you see is the gel.

Radiesse is part filler, part collagen stimulator: The gel gives volume on the day, then absorbs. The calcium particles left behind prompt your skin to lay down its own collagen, so the second half of the result is your tissue rather than the product.

That is why the two behave differently in month three: Voluma looks the same as it did in week two. Radiesse can look flatter for a while, then improve again.

Reversibility is the deciding fact for a first-timer

Voluma can be taken back out: If it is too much, sits wrong or ages badly, an injector can dissolve it in a day or two.

Radiesse cannot be taken back out: There is no antidote, and lumps in this product are the reason that matters. The plan for a poor result is to wait it out.

Lasting longer only helps if you like the result: Starting with a hyaluronic acid gel is the low-risk way to learn what suits your face.

Neither one is a substitute for the other

Radiesse in a cheek is a real option, but a different look: It is stiffer, so it reads as structure rather than softness, and some faces do not suit that in the mid-face.

Voluma along a jawline is also done, and it holds well: The choice there often comes down to how sharp an edge you want and whether reversibility matters to you.

Many people end up with both, in different places: One for the cheek and one for the jaw is a common plan.

What neither one does

Neither one tightens loose skin: Both add volume, and volume added to lax skin usually looks heavy rather than lifted.

Neither one softens a frown line or crow's feet: Those come from muscle movement, and botulinum toxin is the treatment that works on muscle.

Has anyone compared them directly

Not in a way that settles it: Each product has its own studies, usually against a comparison filler in one area. Nobody has run Radiesse against Voluma in the same face and measured which wins, so claims that one beats the other come from clinic experience.

Before you book

Say which area bothers you. Cheek and jaw point to different products.

Ask what happens if you dislike the result. For Radiesse the honest answer is "we wait."

Ask how many syringes the plan needs in total, not the price of one.

Check they keep hyaluronidase on site if Voluma is the plan.

Bring a photo of yourself from a few years ago rather than a photo of someone else.

Related

Questions people ask

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Is Radiesse or Voluma better for cheeks?Voluma is the product designed for cheek volume, and it can be dissolved if you dislike it. Radiesse is used in cheeks too, but it is stiffer and reads more as structure than softness.
Can Radiesse be dissolved?No. There is no enzyme that removes calcium hydroxylapatite. A result you dislike has to be waited out, which takes months.
Which lasts longer, Radiesse or Voluma?Voluma usually lasts longer, up to about two years in the cheek. Radiesse tends to run about a year, though some of the collagen it triggers outlives the product.
Is Radiesse a filler or a collagen stimulator?Both. The gel gives volume on the day, then absorbs. The calcium particles left behind prompt your own collagen, so the later result is your tissue.
Why is Radiesse not used in lips?It has a higher rate of lumps in lip tissue, and those lumps cannot be dissolved. Softer hyaluronic acid gels are used there instead.
Can I have Radiesse and Voluma at the same time?Yes, and it is a common plan. Voluma is often used in the cheek and Radiesse along the jaw, since each suits a different job.