Dermatologist's Take
Soolantra (ivermectin 1% cream) is a strong once-daily prescription for the bumps of rosacea. It fights both inflammation and Demodex mites and works at least as well as metronidazole, but it can be costly and does not cure the condition.
At a glance
- AKA: Soolantra (generic: ivermectin 1% cream)
- Drug Class: Antiparasitic with anti-inflammatory effects
- Rx or OTC: Prescription only
- Typical Strength: 1% cream, applied once a day
- Time to Work: Early change by about 4 weeks; best results by about 12 weeks
- Evidence Level: Strong for papulopustular rosacea. Head-to-head trials show it works at least as well as metronidazole
- Important: Once-daily use is a plus, but it does not cure rosacea.
What is it?
What is it text.
How it works
Ivermectin does two things. It lowers inflammation (skin swelling and irritation) in the skin. It also kills Demodex, a tiny mite that lives on everyone's skin. People with rosacea tend to have more of these mites, and high numbers may trigger flare-ups. Fewer mites plus less inflammation means fewer bumps.
What it treats
How it's typically used
The usual dose is a pea-sized amount spread in a thin layer over the whole face once a day. Avoid the eyes, lips, and inside the nose. Many people use it long-term. This is educational only — follow your prescriber's directions.
Common side effects
- Mild burning or stinging
- Dry skin
- Itching
- Short-lived redness after applying
(These are usually mild and often fade with time.)
Serious side effects
- Strong allergic reaction (swelling, hives, trouble breathing) — rare
- Severe skin irritation
Call your doctor if the skin gets much worse or you have a bad reaction.
Who shouldn't take it
Do not use it if you are allergic to ivermectin or any ingredient in the cream.