Comparison

Benzoyl Peroxide vs Glycolic Acid

Benzoyl peroxide kills the bacteria behind inflamed pimples. Glycolic acid smooths texture and fades marks. Compare results, timing and how to use both.
Written & medically reviewed by the Dermapedia team
At a Glance

Benzoyl peroxide is better for red, inflamed pimples. It kills the bacteria multiplying inside the pore, and it is the strongest acne ingredient you can buy without a prescription. Glycolic acid is better for rough texture, dullness and the marks spots leave behind. It exfoliates the surface. If you are breaking out now, start with benzoyl peroxide. If the spots have gone and the marks have not, start with glycolic acid.

Benzoyl peroxide
Also called BP, BPO, benzoyl peroxide wash
Glycolic acid
Also called AHA, alpha hydroxy acid, glycolic peel

What you do

Once a day, on the whole area

A wash, gel or cream. Treat the region that breaks out, not each spot, because you are preventing the next crop as much as treating this one.

A few nights a week

A toner, serum or pad, usually at night. Some people use a stronger peel in a clinic every few weeks instead.

What you will see

Fewer inflamed spots

Red, sore pimples calm down and fewer new ones appear. The change is in inflammation, not in texture.

Smoother, brighter skin

Softer texture, less dullness, fewer blackheads, and a slow fade of post-acne marks.

What it will not do

It will not smooth texture or fade marks

Benzoyl peroxide does not exfoliate and does not treat pigment. It also does not reach deep cystic lumps.

It will not clear inflamed acne

Glycolic acid is not antibacterial. On angry, inflamed skin it can sting and make redness worse.

How long until it works

Four to six weeks

Some improvement inside two weeks. Judging it earlier than a month is the usual mistake.

Two to four weeks for texture

Brightness comes early. Marks take months.

How long it lasts

As long as you keep using it
As long as you keep using it
Both
Neither is a course you finish. Acne comes back when treatment stops, and dead cells rebuild within weeks.

The downside

Dryness, and it bleaches fabric

Peeling and irritation in the first weeks are common. It also bleaches towels, pillowcases and coloured clothing, permanently.

Stinging and sun sensitivity

It can sting on application and it makes skin more sensitive to sun. Daily sunscreen is not optional with an AHA.

Cost

Inexpensive

One of the cheapest effective acne treatments on the shelf.

Inexpensive at home, more in clinic

Drugstore serums and toners are cheap. A course of in-clinic peels costs considerably more.

The at-home or drugstore version

Drugstore is the real thing

The over-the-counter product is the same ingredient a dermatologist prescribes. Prescription versions mainly combine it with a retinoid or an antibiotic in one tube, for convenience rather than raw power.

Also the same thing, weaker

Drugstore glycolic acid works at the surface. A clinic peel is the same acid, stronger and formulated to go deeper, so it works faster — with a few days of flaking as the trade.

They work on different parts of the problem

Benzoyl peroxide attacks the bacteria inside a blocked pore: It releases oxygen into the pore, and the bacteria involved in acne cannot survive it. That is why inflamed spots settle.

Glycolic acid loosens the dead cells sitting on top of the skin: That smooths the surface and helps keep pore openings clear, but it does nothing to the bacteria below.

Bacteria do not become resistant to benzoyl peroxide: That matters, because they do become resistant to antibiotics. It is a large part of why benzoyl peroxide is still used alongside prescription acne treatment decades on.

Can you use both

Yes, and many people do — just not at the same moment: Benzoyl peroxide in the morning and glycolic acid two or three nights a week is a routine most skin can handle.

Layering them together is where trouble starts: Both are drying. Together, on the same skin, at the same time, they usually cause more irritation than either one earns you.

Irritated skin looks like worse acne: Redness, flaking and stinging get read as a failed treatment. Usually it means too much, too fast.

Getting the most out of benzoyl peroxide

A wash left on for a minute before rinsing is a good starting point: It gives you the effect with less of the dryness a leave-on gel causes.

Use white towels and old pillowcases: The bleaching is not a rumour and it is not reversible.

Moisturize on top: The people who stick with benzoyl peroxide are almost always the ones who moisturize alongside it.

Before you start either one

Pick one and give it six weeks before deciding whether it works

Start every other day rather than daily, on the whole area rather than on spots

Pair either one with a plain moisturizer from day one, not after the peeling starts

Wear sunscreen every morning — mandatory with glycolic acid, sensible with both

Do not add a third active in the same fortnight, or you will not know what caused what

See a dermatologist if the spots are deep, painful lumps, since neither product reaches them

Related

Questions people ask

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Which is better for acne, benzoyl peroxide or glycolic acid?
Benzoyl peroxide, for inflamed spots. It kills the bacteria in the pore. Glycolic acid exfoliates the surface and helps texture and post-acne marks instead.
Can I use benzoyl peroxide and glycolic acid together?
Yes, but not layered at the same time. Benzoyl peroxide in the morning and glycolic acid two or three nights a week is easier on the skin.
Does benzoyl peroxide really bleach fabric?
Yes, and permanently. Use white towels and pillowcases, and be careful with coloured clothing.
How long before benzoyl peroxide works?
Four to six weeks for a fair judgement, though some improvement usually shows within two. Stopping at two weeks is the most common mistake.
Will glycolic acid fade dark marks from acne?
Slowly. It speeds up how fast marked surface cells are shed, so expect months rather than weeks — and wear sunscreen, since it increases sun sensitivity.
Why is my skin worse since I started?
Dryness, flaking and redness in the first weeks are common with both and often read as worsening acne. Use less, less often, and moisturize.