RESEARCH STUDY

Ivermectin keeps rosacea clear longer than metronidazole (ATTRACT, 2016)

2016
RCT
764
High

One-line finding

Ivermectin cream kept rosacea clear longer than metronidazole after treatment stopped.

Plain-language summary

People whose rosacea bumps cleared were followed after stopping treatment. Those who had used ivermectin cream stayed clear longer (about 115 days before relapse) than those who used metronidazole (about 85 days). Both were safe. This helped establish ivermectin as a strong first-line option for the bump-and-pimple form of rosacea.

Citation

Taieb A, Khemis A, Ruzicka T, et al. Maintenance of remission following successful treatment of papulopustular rosacea with ivermectin 1% cream vs. metronidazole 0.75% cream: 36-week extension of the ATTRACT randomized study. J Eur Acad Dermatol Venereol. 2016;30(5):829-836.
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