RESEARCH STUDY

Ivermectin vs azelaic acid: 1-year safety in rosacea (2014)

2014
RCT
Moderate

One-line finding

Ivermectin 1% cream stayed safe and effective for up to a year of treatment.

Plain-language summary

These extension studies followed rosacea patients for a full year of treatment. Ivermectin cream kept reducing bumps and pimples and had fewer treatment-related side effects than azelaic acid gel. The results support using ivermectin as a safe long-term therapy for the bump-and-pimple form of rosacea. (Industry-funded.)

Citation

Stein Gold L, Kircik L, Fowler J, et al. Long-term safety of ivermectin 1% cream vs azelaic acid 15% gel in treating inflammatory lesions of rosacea: results of two 40-week controlled, investigator-blinded trials. J Drugs Dermatol. 2014;13(11):1380-1386.
Read the study
ermapedia is for education only and is not medical advice. It does not create a doctor–patient relationship. Always consult a qualified clinician about your own skin.

Dermapedia

The science-based skin encyclopedia.

Reviewed by a board-certified dermatologist

Dermapedia is for education only and is not medical advice. It does not create a doctor–patient relationship. Always consult a qualified clinician about your own skin.

© 2026 Dermapedia · Privacy · Terms

DermaPedia

The science-based skin encyclopedia.

Reviewed by a board-certified dermatologist

Dermapedia is for education only and is not medical advice. It does not create a doctor–patient relationship. Always consult a qualified clinician about your own skin.

© 2026 Dermapedia · Privacy · Terms

Derma

Pedia

The science-based skin encyclopedia.

Reviewed by a board-certified dermatologist

SkincareRetinolVitamin CNiacinamideHyaluronic acidView all →
ConditionsAcneEczemaRosaceaDandruffView all →
MedicationsIsotretinoinDoxycyclineSpironolactoneMinoxidilView all →
CosmeticsBotoxDermal fillersChemical peelMicroneedlingView all →

More

CompareStudiesAboutEditorial policy

Dermapedia is for education only and is not medical advice. It does not create a doctor–patient relationship. Always consult a qualified clinician about your own skin.

© 2026 Dermapedia ·

Privacy

·

Terms