RESEARCH STUDY

Rosacea treatments: systematic review with GRADE (2019)

2019
Meta-analysis
20944
High

One-line finding

Strong evidence supports topical brimonidine for redness and azelaic acid and ivermectin for bumps and pimples.

Plain-language summary

Researchers combined results from 152 trials to see which rosacea treatments work best. For temporary redness, brimonidine gel had the strongest evidence. For bumps and pimples, azelaic acid and ivermectin creams and low-dose doxycycline worked well. For visible blood vessels, laser and intense pulsed light helped. This review underpins today's treatment guidelines.

Citation

van Zuuren EJ, Fedorowicz Z, Tan J, et al. Interventions for rosacea based on the phenotype approach: an updated systematic review including GRADE assessments. Br J Dermatol. 2019;181(1):65-79.
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